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  • Haogang Cai

11/20/2019

Updated: Mar 12, 2020

Our paper "Integrin nanoclusters can bridge thin matrix fibres to form cell–matrix adhesions" is commented in Nature Materials. "This study demonstrates that single thin fibres are unable to support adhesion of cells even with sufficient ligand density; rather, they support transient adhesion events. Instead, adhesion is better supported when fibres are in parallel, are crossing or are wide enough, highlighting the significance of matrix geometry. Moreover, the role of adhesion proteins such as focal adhesion kinases, talins and integrins in the context of cell adhesion are also highlighted in this study. This work will stimulate further research in the field of material science and mechanobiology, ..." Read more

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Dr. Cai gave an invited talk "Nanoengineered biomimetic interfaces for T cell mechanobiology study" at the WE-Heraeus-Seminar "Nanobiotechnology for Cell Interfaces". https://www.we-heraeus-stiftung.d